1. Eight or more ear infections within 1 year

2. Two or more serious sinus infections within 1 year

3. Two or more months on antibiotics with little or no affect

4. Two or more pneumonias within 1 year

5. Failure of an infant to gain weight or grow normally.

6. Recurrent, deep skin or organ abscesses.

7. Persistent thrush in mouth or elsewhere on skin, after age 1.

8. Need for intravenous antibiotics to clear infections.

9. Two or more deep seated infections

10. A family history of primary immune deficiency.

These warning signs were developed by the Jeffrey Modell Foundation Medical Advisory Board